AMBISOME PACKAGE INSERT PDF

Name of the medicinal product. AmBisome 50 mg Powder for solution for infusion . 2. Qualitative and quantitative composition. Each vial contains 50 mg of. The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a. AmBisome is given as an infusion into a vein (a drip) by a doctor or nurse. . Package leaflet: information for the user. AmBisome®. Liposomal.

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The majority of clinically important fungal species seem to be susceptible to amphotericin B, although intrinsic resistance has rarely been reported, for example, for some strains of S.

L-AmB has been shown to be effective in animal models of visceral leishmaniasis caused by Leishmania infantum and Leishmania donovani. In a double-blind study involving packagd, the incidence of nephrotoxicity with AmBisome as measured by serum creatinine increase greater than 2. Although infusion-related reactions are not usually serious, consideration of precautionary measures for the prevention or treatment of these reactions should be given to patients who receive AmBisome therapy.

Allergic type reactions, including severe infusion-related reactions can occur during administration of amphotericin-containing products, including AmBisome see section 4.

All are known targets for amphotericin B toxicity. Back to top Gilead Sciences Ltd contact details.

Where these symptoms were noted, reaction developed within a few minutes after the start of infusion and disappeared rapidly when the infusion was stopped. Data suggest that no dose adjustment is required in patients undergoing haemodialysis or filtration procedures, however, L-AmB administration should be avoided during the procedure.

L-AmB was found to be non-mutagenic in bacterial and mammalian systems.

Marketing authorisation holder 8. The pharmacokinetic profile of AmBisome liposomal amphotericin B L-AmBbased upon total plasma concentrations of amphotericin B, was determined in cancer patients with febrile neutropenia and bone marrow transplant patients who received 1 hour infusions of 1.

ambisoem No studies on the effects on the ability to drive and use machines have been performed. Please see full Prescribing Information. Antifungals No evidence of benefit from the use of flucytosine with AmBisome has been observed. Both systemic fungal infections in children and presumed fungal infections in children with febrile neutropenia have been successfully treated with AmBisome, without reports of unusual adverse events.

Renal function should be closely monitored in these patients. Hepatic impairment Packsge data are available on which to make a dose recommendation for patients with hepatic impairment See section 4. Am B pacakge is indicated for the following:. Summary of adverse reactions The following adverse reactions have been attributed to AmBisome based on clinical trial data and post-marketing experience. Within each frequency grouping, undesirable effects are presented in order inset decreasing seriousness.

AmBisome and Micafungin were administered for a median duration of 15 days. Regular monitoring of renal function is recommended in patients receiving AmBisome with any nephrotoxic medications.

Any unused product or waste material should be disposed of in accordance with local requirements. Concurrent use of corticosteroids, ACTH and diuretics loop and thiazide may potentiate hypokalemia. Concurrent use of antineoplastic agents may enhance the potential for renal toxicity, bronchospasm and hypotension.

In addition, infusion-related reactions may also be prevented by the use of premedication. The molecule is thought to pxckage by binding to sterols in the fungal cell membrane, with a resulting change in membrane permeability, allowing leakage of a variety of small molecules.

Reporting suspected adverse reactions after authorisation of the medicinal product is important.

AmBisome – Summary of Product Characteristics (SmPC) – (eMC)

Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity see section 5. It is unknown whether AmBisome is excreted in human breast milk.

AmBisome must be reconstituted by suitably trained staff. Renal toxicity AmBisome has been shown to be substantially less toxic than conventional amphotericin B, particularly with respect to nephrotoxicity; however, renal adverse reactions may still occur. AmBisome-induced hypokalemia may enhance the curariform effect of skeletal muscle relaxants e.

Paediatric population Both systemic fungal infections in children and presumed fungal infections in children with febrile neutropenia have been successfully treated with AmBisome, without reports of unusual adverse events. Warnings and Precautions Anaphylaxis has been reported with amphotericin B—containing drugs, including Am B isome. These studies include comparative randomized studies of AmBisome versus conventional amphotericin B in confirmed Aspergillus and Candida infections where the efficacy of both medicinal products was equivalent.

However, the following medicinal products are known to interact with amphotericin B and may interact with AmBisome: Treatment should be continued until the recorded temperature is normalised for 3 consecutive days. The effect of renal impairment on the pharmacokinetics of L-AmB has not been formally studied.

However, the mean pore diameter of the filter should not be less than 1. Enter medicine name or company Start typing to retrieve search suggestions. This site uses cookies. AmBisome should only be used during pregnancy if the possible benefits to be derived outweigh the potential risks to the mother and fetus. The efficacy of AmBisome in the treatment of visceral leishmaniasis has been clearly demonstrated in a large population of immunocompetent and immunocompromised patients.

Clinical efficacy and safety The efficacy of AmBisome has been established in a number of clinical trials for the treatment of systemic mycotic infections, as empirical therapy for fever of unknown origin in neutropenic patients and for the treatment of visceral leishmaniasis. The use of any solution other than those recommended, or the presence of a bacteriostatic agent e.

Amphotericin B for Injection, USP

Very common Common Uncommon Very rare. Active ingredient amphotericin b. Pregnancy The ambisomd of AmBisome in pregnant women has not been established. For a full list of excipients, see section 6. Fertility Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity see section 5.

Some of the undesirable effects of AmBisome presented below may impact the ability to drive and use machines.

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I carmi di Caio Valerio Catullo di Catullus, Gaius Valerius e una grande selezione di libri, arte e articoli da collezione disponibile su Donor challenge: Your generous donation will be matched 2-to-1 right now. Your $5 becomes $15! Dear Internet Archive Supporter,. I ask only. – Buy I Carmi Di Caio Valerio Catullo book online at best prices in India on Read I Carmi Di Caio Valerio Catullo book reviews.

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Il sinus infatti era il lembo a catuullo della veste. Solitamente si colloca questo passo all’inizio catmi per Lesbia dove tale sentimento era ancora forte e si vedeva solo in lontananza che sarebbe diventato tragico. La cena a roma si svolgeva verso il tramonto e corrispondeva al nostro pranzo. Apparteneva a una famiglia agiata. Era la fiaccola che serviva a far luce durante la notte mentre si svolgeva la deductio. Dativi retti da libet.

Carmi – Catullo

Appaiono infatti in essi particolarmente forti gli influssi della poetica di Ennio, dell’epica e della tragedia arcaica in campo latino, ma soprattutto dei poeti ellenistici in campo greco. Il libraio ha consegnato a Catullo il rotolo di papiro ben levigato e il poeta, contento e soddisfatto, lo ammira e si domanda con una punta di orgoglio a chi donarlo se non a Cornelio che aveva apprezzato un tempo le sue nugae. Tra l’altro si nota anche per la struttura tonale lenta e pacata con datullo tre spondei iniziali.

Manlio Torquato pretore nel 49 e seguace di Pompeo morto in Africa nel Si noti la contrapposizione con spectat del v.

Sia il saltellare che questi suoni fanno immaginare un Catullo che rivive nella mente quei momenti passati. Dativo retto da nubet. La dedica era una moda a Roma derivata dai poeti alessandrini. Con l’intento di creare un effetto di marcato contrasto, Catullo affianca a tali elementi del linguaggio colloquiale alcune forme e usi propri del linguaggio letterario, come le allusioni, tipiche della letteratura alessandrina, gli epiteti di stampo epico, spesso ricalcati dal greco, gli arcaismi ispirati al linguaggio di Omero ed Ennio.

Molti di essi sono dedicati ad amici scrittori e lasciano intravedere uno spicchio di vita quotidiana che il poeta conduceva a Roma, e soprattutto i rapporti con la cerchia dei neoterici.

Menu di navigazione Strumenti personali Accesso non effettuato discussioni contributi registrati entra. Il dramma sta nel fatto che l’Odio e l’Amore non hanno sbocchi. Ha valore di perfetto altrimenti non si spiegano i due congiuntivi imperfetti dei versi successivi.

Classico Latino: Catullo (superiori) – Wikiversità

Manlio Torquato e Vinia Aurunculeia. Verbo integrato al codice dall’Avantius. Tipico costrutto di Catullo. Chi legge acquiescit e chi acquiescat. Il contrasto faciam-fieri esprime la condizione di attore e vittima allo stesso tempo del poeta. Esprime la passivita e stanchezza del poeta. Letteratura latina per le superiori 1 Cadmi latina per le superiori 2 Letteratura latina per le superiori 3.

In altre lingue Aggiungi collegamenti. Gli animali sono un oggetto poetico molto cqtullo dalla poesia ellenistica. Il congiuntivo si spiega con il carattere eventuale dell’azioni nelle due strofi precedenti invece l’uso dell’indicativo denotava azioni reali. Questo ha fatto pensare che in questa fase l’amore fosse anche contraccambiato e il dolore di Lesbia sia il dolore anche di Catull. Le ragazze portvano fino al giorno del matrimonio una cintura che chiudeva la scollatura delal veste sul petto.

L’assenza dell’oggetto per i due verbi assumono valore intransitivo e rappresentano lo spirito del poeta. L’ultimo componimento racconta della vicenda mitica riguardante Protesilao e Laodamia, il quale riassume bene i due temi principali della poesia catulliana di questo periodo, ovvero la morte di un congiunto la scomparsa del fratello e l’amore disperato e carnale la passione per Lesbia.

Va collegato al te di v. Essere al verde per Catullo e i suoi amici era un fatto comune vivendo una vita da bohemiens.

Comunque la quarta strofa denota una personalizzazione da parte catullk Catullo del componimento della poetessa. Di conseguenza, anche il lessico appare particolarmente ampio, tanto da accogliere assieme forme oscene e volgari, diminutivi, grecismi, interiezioni, onomatope ed espressioni idiomatiche o proverbiali. In ottemperanza al criterio callimacheo della poikilia varietas in latino: Dono ha doppia costruzione o aliquem aliqua re o come qui alicui aliquid.

Car,i sta per petto con significato chiaramente metonimico. Nella prima parte vv. Sono finite le scene di vita e di amore e comincia la morte e il pianto.

Poi ci sono le lodi al dio che sono un inno all’amore vv. Risorse non curate da nessun dipartimento. Espressione usata anche da Foscolo che rende in modo completo la visione meccanicistica della vita senza nessuna visione escatologica e spirituale.

Carmi – Catullo – Tallone Editore Shop

Nella terza parte vv. Non mancano, tuttavia, elementi afferenti al linguaggio colloquiale, in particolare i diminutivi. Da notare l’insistenza sul riferimento temporale quasi a voler fissare in una data storica i primi elogi da parte del dotto amico. Accostamento di particolare efficacia che ha quasi la forza di un ossimoro. Catullo con questo breve componimento riesce a creare un ritmo spezzato e lento con due versi e tre periodi.

Nella seconda parte vv.

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Software Testing: An ISTQB-BCS Certified Tester Foundation Guide 3rd ed By Brian Hambling Software Testing: An Iseb Intermediate Certificate (1st Edition). Brian Hambling is the author of Software Testing ( avg rating, 24 ratings, 1 review, published ), Software Testing ( avg rating, 20 ratings. Brian Hambling has 13 books on Goodreads with ratings. Brian Hambling’s most popular book is Software Testing: An ISTQB-ISEB Foundation Guide.

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DS-3053: Statement of Consent or Special Circumstance for a Minor Passport

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I was wondering what my best options are. You may fill out these forms using an online form filler or by downloading a PDF of the application and handwriting on it in black ink.

AKAMAI STATE OF THE INTERNET Q2 2012 PDF

This issue of the State of the Internet report marks the beginning of the fifth year of the report’s publication. . In the first quarter of , average connection speeds on and the seasonal slowdown in growth observed in Q2 has. this issue of the State of the Internet Report marks the end of five years of publication — the works all over the world between Q2 and Q1 only. United States Average Peak Connection Speeds. 15 . With the 4th Quarter, State of the Internet Report, Akamai Q2. ‘ Q3. ‘ Q4. ‘ Q1. ‘ Total (UL + DL) monthly traffic (PetaByes/month). Data. Voice.

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Akamai Technologies – Wikipedia

These servers reside in more than 1, [14] of the world’s networks gathering real-time information about traffic, congestion, and trouble spots. Meanwhile the average broadband speed in the UK stands at 5.

Retrieved on August 14, The latest Akamai report on the state of the internet is out, and it looks like DDoS attacks have spiked since or last one. We initially reported that DDoS attacks had dropped since Q1though in fact the report shows they have increased. Archived March 31,at the Wayback Machine. Business data for Akamai Technologies: Dzwonczyk asserts that the patent claim “could easily have been rewritten as a single-actor method claim that would not require the performance of any step by a second actor,” knternet provides a rewritten version.

Receiving content from an Akamai server close to the user allows for faster download times and less vulnerability to network congestion. We’re using cookies to improve your experience.

Quick African facts from Akamai’s ‘The State of the Internet, Q2 ′ Report – oAfrica

When a user navigates to the URL of an Akamai customer, their browser is redirected to one of Akamai’s copies of the website.

Added to the Russell Index and Russell Index”. Archived from the original on May 15, China is in second place with 33 percent down from 34 percentfollowed by the U. InPaul Sagan was named chief executive officer of Akamai. China’s traffic dropped from 34 percent to 33 percent, but combined, the two countries still comprise more than half of observed attack traffic.

The Akamai server is automatically picked depending on the type of content and the user’s network location. In the United States, the average connection speed is 8.

October 17, at 2: Thf State of the Internet report is a quarterly report Akamai releases based on data gathered from its Intelligent Platform, which provides global Internet statistics such as connection speedbroadband adoption, attack trafficnetwork connectivity, and mobile connectivity. Archived from the original on January 18, In other projects Wikimedia Commons. Conrades became the chief executive officer fo Akamai in April and led the company from start-up to sustained profitability and positive free cash-flow before turning the reins over to Sagan in Speed 30Mbps, Unlimited Gift: Archived from the original on January 22, Beijing uses face-detecting smart locks to curb public housing abuses.

Mobile Connectivity During the second quarter ofaverage connection speeds on surveyed mobile network operators ranged from a a,amai of 9.

Akamai Technologies

Global internet interney rose at a much higher rate since the last report. Highlights include the inhernet in worldwide connection speeds and the huge increase of “attack traffic” originating in Indonesia.

Looking at global average mobile connection speeds, they ranged from 0. It said that “Akamai presented substantial evidence demonstrating that Limelight conditions its customers’ use of its content delivery network upon its customers’ performance of” the steps that Limelight does not itself perform. Year-over-year, global average peak connection speeds continued to demonstrate solid growth, rising 17 percent.

Your browser does not support iframes. Lewin died in the September 11th attacks at the age of In late and earlya group of business professionals joined the founding team.

From around the web. Retrieved June 19,

IL GLADIATORE SOUNDTRACK PDF

Check out Now We Are Free (Il Gladiatore Soundtrack) by Cicci Guitar Condor on Amazon Music. Stream ad-free or purchase CD’s and MP3s now on. Check out Il gladiatore invincibile (Original motion picture soundtrack) by Carlo Franci on Amazon Music. Stream ad-free or purchase CD’s and MP3s now on. The Gladiator Complete Soundtrack Music – Il Gladiatore Colonna Sonora Completa. Gladiator Soundtrack-Now We Are Free-composed by Hans Zimmer.

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Dawn of Justice Blade Runner Views Read Edit View history.

IL GLADIATORE INVINCIBILE

Discography Remote Control Productions. In Aprila law firm representing the Holst Foundation filed a lawsuit claiming that Zimmer had infringed the copyright of Gustav Holst ‘s The Planets. Hans Zimmer’s style influenced ssoundtrack composers, who used elements like female wailing vocals and the “battle waltz” for ancient war movies that followed. Recording Industry Association of America.

Still, there is so much drama vladiatore just the song. Dead Man’s Chest Pirates of the Caribbean: This page was last edited on 15 Octoberat Hans Zimmer and Lisa Gerrard. From Wikipedia, the free encyclopedia. Gladiator is the original soundtrack of the film of the same name.

Federazione Industria Musicale Italiana.

Gladiator (soundtrack) – Wikipedia

Select Silver in the Certification field. Select albums in the Format field.

Archived from the original on It’s a magnificent song and a tough movie. Stallion of the Cimarron Pirates of the Caribbean: Retrieved 20 October Retrieved from ” https: Retrieved 22 April More Music From the Motion Picture. On Stranger Tides Sherlock Holmes: Music From the Motion Picture.

Polish Society of the Phonographic Industry. The song was based on a theme from the score, featured on the soundtrack as track 4, “Earth”. Hans Zimmer soundtracks soundtracks soundtracks Gladiator film Lisa Gerrard albums. Retrieved July 26, Music from the Movies.

On February 27,nearly a year after the first soundtrack’s release, Decca released Gladiator: The original score and songs were composed by Hans Zimmer and Lisa Gerrard and were released intitled Gladiator: The Lyndhurst Orchestra performing the score was conducted by Gavin Greenaway. Select Platinum in the Certification field.

For the film’s 5 year anniversary a double CD edition was released combining the 2 gladiatoge editions. Retrieved 27 June By using this site, you agree to the Terms of Use and Privacy Policy.

Many tracks also use dialogue from the movie, such as Maximus Decimus Meridius’ quote “Father to a gladiwtore son, husband to a murdered wife Pavarotti told Billboard magazine that he was meant to sing this song in the film, “But I said no then.

GLLAMM MANUAL PDF

Documentation on gllamm. A book on gllamm, xtmixed, xtlogit, xtprobit, xtpoisson, etc., xtmelogit, and xtmepoisson for multilevel The gllamm manual. gllamm — Generalized linear and latent mixed models about gllamm by visiting A Handbook of Statistical Analyses Using Stata. gllamm now consists of a model fitting program, and post-estimation and simulation programs gllapred and gllasim. • gllamm and gllamm manual, datasets and.

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Generalised, linear, latent and mixed models. Categorical Responses, Counts, and Survival Datasets and do-files Reviews A companion for Volume I of the book above, demonstrating how most of the models can be estimated using gllamm The gllamm companion for Rabe-Hesketh, S. Get my own profile Cited by View all All Since Citations h-index 69 46 iindex Gklamm combined citations are counted only for majual first article. Cognition 78 1B1-B15 A Short Introduction to Stata for Biostatistics.

GLLAMM: what effect size metric is in the output? – Statalist

The data are all in a zip file Individual data files are also available: A companion for Volume I of the book above, demonstrating how most of the models can be estimated using gllamm The gllamm companion for Rabe-Hesketh, Ggllamm.

A book on gllammxtmixedxtlogitxtprobitxtpoissonetc.

I am now a bit confused and hope someone can help me with this: Childhood obsessive-compulsive personality traits in adult women with eating disorders: Magnetic resonance imaging 15 glla,m, Includes chapter on random effects modeling using gllamm. American Journal of Psychiatry 1, I have been working with GLLAMM to conduct multilevel multinomial logistic regression analyses 4 categorical outcome options, with ‘study’ as an additional level in these analyses.

Publications on specific models or methods implemented in gllamm.

glllamm Structural equation models KA Bollen Encyclopedia of biostatistics 7 Generalized latent variable modeling: Multilevel, Longitudinal, and Structural Equation Models.

Links to many Stata Resources at Stata website.

New articles by this author. Generic brain activation mapping in functional magnetic resonance imaging: Systematic review and meta-analysis of randomised controlled trials of psychological interventions to improve glycaemic control in patients with type 2 diabetes K Ismail, K Winkley, S Rabe-Hesketh The Lancet, New articles related to this author’s research.

Estimates are transformed only in the first equation.

Primer on gllamm

Email address for updates. You might consider meologit for example. Verified email at berkeley. Everything works as it should, but I’m not so sure what the effect size metric is in the output. You’ll increase your chances of a useful answer by following the FAQ on asking yllamm – provide Stata code in code delimiters, readable Stata output fixed spacing fonts helpand data using dataex.

My profile My library Metrics Alerts. Generalized Latent Variable Modeling: Social statistics biostatistics psychometrics statistical models latent variable models. In the Table, it says ‘Coef.

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Reliable estimation of generalised linear mixed models using adaptive quadrature. Journal of the Royal Statistical Society: Stata Technical Bulletin 53 Search in titles only.

gllammm I have done that, but I’m most interested in Relative Risk Ratios rrr. Many of gllamm’s functions are available in other routines. Thank you very much in advance! I don’t use gllamm so I can’t help you with the issue per se.